Medicine Supply Notification: DDAVP (Desmopressin) 0.01% w/v (100 micrograms/ml) intranasal solution – Updated

Update: (08/11/2021) This product has now been discontinued 


Department of Health and Social Care (DHSC) has issued a medicine supply notification for DDAVP (Desmopressin) 0.01% w/v (100 micrograms/ml) intranasal solution

DDAVP (Desmopressin) 0.01% w/v (100 micrograms/ml) intranasal solution will be out of stock from the end of October until mid 2021

Supplies of generic Desmopressin 100 micrograms/ml nasal spray (10 micrograms per actuation) listed on NHS Dictionary of Medicines and Devices (dm+d) as ‘Desmopressin 10micrograms/dose nasal spray’  remain available from Aspire Pharma Ltd and can fully support demand during this time for patients on doses ≥10 microgram.

Desmopressin tablets and oral lyophilisates remain available.

Unlicensed imports of Desmopressin 100 micrograms/ml intranasal solution can be sourced. There is currently no listing on dm+d for the imported product for prescribers to select using their prescribing systems so an EPS prescription for unlicensed Desmopressin 100micrograms/ml intranasal solution cannot be issued. Where a prescriber wishes to prescribe an unlicensed import, an FP10 paper prescription should be issued as ‘Desmopressin 100 micrograms/ml intranasal solution (Special Order)‘ and endorsed by the pharmacy as a non-Part VIIIB special with the following information:

  • Amount dispensed over pack size used;
  • Invoice price per pack size from which the order was supplied less any discount or rebate;
  • Manufacturers’/importers’ MHRA licence number;
  • Batch number of the product supplied;
  • Initials ‘SP’

The DHSC Medicine Supply Team provide a monthly update on potential supply issues affecting both primary and secondary care. This update is uploaded on the Specialist Pharmacy Services (SPS) website. To register, you will need  an NHS email address. Once set up and logged in, you will be able to access it online.

New shortages not listed on the SPS website, can be reported using our shortage reporting tool.