Entresto (sacubitril valsartan) – significant event


An incident has recently been reported to Sunderland CCG MO team when a patient was admitted to hospital and was found to have a compliance aid with Entresto (sacubitril valsartan) dispensed into it.

We have been asked by the cardiology team to highlight that Entresto should not be dispensed into a compliance aid. The SPC states the following:

6.4 Special precautions for storage
This medicinal product does not require any special temperature storage conditions.
Store in the original package in order to protect from moisture

This information is also included in the published document, available at:

www.sunderlandccg.nhs.uk/wp-content/uploads/2017/03/Entresto-information-leaflet-for-primary-care-V1-extended-approval-date.pdf